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Health Library

Our Health Library information does not replace the advice of a doctor. Please be advised that this information is made available to assist our patients to learn more about their health. Our providers may not see and/or treat all topics found herein.

Mononucleosis spot test

A mononucleosis spot test (rapid mono test) is a screening test for mononucleosis. The test detects a type of antibody (heterophil antibody) that forms during certain infections, especially during infection with the Epstein-Barr virus.

For this test, a sample of blood is placed on a microscope slide and mixed with other substances. If heterophil antibodies are present, the blood clumps. This result usually points to a mono infection.

The test can usually find a mono infection in about 2 to 9 weeks after the person has been exposed to the virus. The antibodies are proteins made by the immune system to fight the infection. After they have formed, antibodies usually remain in a person's blood for life.

Current as of: April 30, 2024

Author: Ignite Healthwise, LLC Staff

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All Healthwise education is reviewed by a team that includes physicians, nurses, advanced practitioners, registered dieticians, and other healthcare professionals.